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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 17.88
Human Site: S275 Identified Species: 30.26
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S275 S S L R N Q L S S Q K S V P W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S275 S S L R N Q L S S Q K S V P W
Dog Lupus familis XP_532204 495 54438 S275 S S L K N Q L S S Q K S V P W
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S275 S S L K N Q L S S Q K V V P W
Rat Rattus norvegicus Q7TSF2 588 64736 N296 T S I G E G A N L A S L S K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 I259 S L P L S G L I C F Y M N W I
Chicken Gallus gallus NP_001026257 484 53539 S264 S S L K D Q L S T Q K S V P W
Frog Xenopus laevis Q6INC8 576 63887 G283 E S I G E S T G F M N P M A K
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 N296 T S I G E G A N L M S S T E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 V280 S L W G T D V V K S P P I P F
Honey Bee Apis mellifera XP_395682 508 56831 E274 N S L G N L K E E K I K H P W
Nematode Worm Caenorhab. elegans Q03567 493 52719 W264 G K V P S T P W I K I L T S P
Sea Urchin Strong. purpuratus XP_780445 542 58846 P278 F L Q K A I K P R D K Y N Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 P337 G G S K P R E P V T V I P W K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 6.6 N.A. 13.3 80 6.6 13.3 N.A. 13.3 33.3 0 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 33.3 N.A. 20 100 20 33.3 N.A. 33.3 46.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 15 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 0 22 0 8 8 8 0 0 0 0 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 8 8 0 0 0 0 15 % F
% Gly: 15 8 0 36 0 22 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 22 0 0 8 0 8 8 0 15 8 8 0 8 % I
% Lys: 0 8 0 36 0 0 15 0 8 15 43 8 0 8 22 % K
% Leu: 0 22 43 8 0 8 43 0 15 0 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 15 0 8 8 0 0 % M
% Asn: 8 0 0 0 36 0 0 15 0 0 8 0 15 0 0 % N
% Pro: 0 0 8 8 8 0 8 15 0 0 8 15 8 50 8 % P
% Gln: 0 0 8 0 0 36 0 0 0 36 0 0 0 8 0 % Q
% Arg: 0 0 0 15 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 50 65 8 0 15 8 0 36 29 8 15 36 8 8 8 % S
% Thr: 15 0 0 0 8 8 8 0 8 8 0 0 15 0 0 % T
% Val: 0 0 8 0 0 0 8 8 8 0 8 8 36 0 0 % V
% Trp: 0 0 8 0 0 0 0 8 0 0 0 0 0 15 43 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _